2026
Nagornîi, D.; Valdés-Maqueda, Á.; Stocchetti, S.; Kaplaneris, N.; He, Z. and Noël, T. Late-Stage Aryl NCF₃ and SCF₃ Installation Enabled by Coupling Flow-Generated Anions with Aryl Thianthrenium Salts ChemRxiv, 2026, DOI: 10.26434/chemrxiv.15000577/v1
Tiwari, P.; Liu, R. and Noël, T. Direct δ-Lactone Synthesis from Free Alcohols via Photoinduced δ-C(sp³)-H Carbonylation in Flow ChemRxiv, 2026, DOI: 10.26434/chemrxiv.15000557/v1
Schuurmans, J. H. A.; Lukas, F.; Tiwari, P. C. and Noël, T. Photon Management in Photochemical Synthesis and Reactor Scale-Up Accounts of Chemical Research, 2026, 59, 788-801, DOI: 10.1021/acs.accounts.5c00885
Belnome, F.; Pulcinella, A.; Bonciolini, S.; Lepori, M.; Datsenko, O. P.; He, Z.; Gasparetto, M.; Mykhailiuk, P. K.; De Bruin, B. and Noël, T. A C_1 -Homologative Trifluoromethylation: Light-Driven Decarboxylative Trifluoroethylation of Carboxylic Acids Journal of the American Chemical Society, 2026, 148, 7645-7654, DOI: 10.1021/jacs.5c21423
Findlay, M. T.; Lukas, F.; Yamazaki, K.; Hopsort, G.; Martin, B.; Allmendinger, S.; Furegati, M.; Gabriel, P.; Tiekink, E. H.; Hamlin, T. A. and Noël, T. Decoding C-O vs C-C Bond Selectivity in Nickel-Metallaphotoredox Carboxylic Acid Cross-Coupling ChemRxiv, 2026, DOI: 10.26434/chemrxiv.10002040/v1
Schuurmans, J. H. A.; Zondag, S. D. A.; Chaudhuri, A.; Van Der Schaaf, J. and Noël, T. Stirring the Debate: How Mixing Influences Reproducibility and Efficiency in Synthetic Organic Chemistry ACS Central Science, 2026, 12, 7-13, DOI: 10.1021/acscentsci.5c01825 (For the preprint version, see 10.26434/chemrxiv-2025-1m8pt)
2025
Schuurmans, J.; Claros, M.; Savino, E.; Lukas, F.; Slattery, A. and Noel, T. Closed-Loop Photoreactor Design Enabled by Machine Learning and Digital Twins ChemRxiv, 2025, DOI: 10.26434/chemrxiv-2025-s7b3k
Djossou, J.; Pasca, F.; Akdeniz, M.; Bonciolini, S.; Pulcinella, A.; Bayley, O.; Johansson, M.; Colella, M.; Luisi, R. and Noel, T. Radical Disconnection Logic Enables Direct Conversion of α-Amino Acids into Differentiated Vicinal Diamines ChemRxiv, 2025, DOI: 10.26434/chemrxiv-2025-l7skx
Nagornîi, D.; Ronco, P.; Anwar, K.; Kaplaneris, N.; Douglas, J. J. and Noël, T. Flow-Enabled, Modular Access to α,α-Difluoromethylene Amines Angewandte Chemie International Edition, 2025, 64, e17282, DOI: 10.1002/anie.202517282 (For the preprint version, see 10.26434/chemrxiv-2025-z4lnw)
Gasparetto, M.; Sveiczer, A.; Fermi, A.; Raji, M.; Fair, R. J.; Noël, T.; Ceroni, P. and Sipos, G. In Situ Generated Triazine Co-Catalyst Unlocks Amidine Arylation under Dual Nickel/Photoredox Catalysis: A Platform for Mild C–N Bond Formation ACS Catalysis, 2025, 15, 21213-21223, DOI: 10.1021/acscatal.5c07508
Gasparetto, M.; Bonciolini, S.; Diprima, D.; Pulcinella, A.; Gabbey, A. L.; Datsenko, O. P.; Belnome, F.; Schuurmans, J. H. A.; Mykhailiuk, P. K. and Noël, T. Glyoxylate Sulfonyl Hydrazone Enables a Scalable Approach to Reformatsky-Type Products from Aliphatic Alcohols via Photocatalytic HAT Organic Letters, 2025, 27, 13649-13654, DOI: 10.1021/acs.orglett.5c04616
Ioannou, D. I.; Bombonato, E.; Sanramat, J.; Reek, J. N. H. and Noël, T. Oxidant-Free Amidation of Aldehydes Enabled by Electrophotocatalysis Chemistry – A European Journal, 2025, 31, e02237, DOI: 10.1002/chem.202502237 (For the preprint version, see 10.26434/chemrxiv-2025-v1jd8)
Kaplaneris, N.; Savino, E.; He, Z.; Stini, N.; Vanzella, M.; Fillols, M.; Siasiaridis, P.; Bayley, O.; Halskov, K.; Hogendorf, W.; Wojcik, F.; Kokotos, C. and Noel, T. Machine Learning-Guided Discovery of Robust Conditions for Photochemical Nickel-Catalyzed Cysteine Arylation ChemRxiv, 2025, DOI: 10.26434/chemrxiv-2025-zwqnt
Diprima, D.; Paulsen, T. T.; Pulcinella, A.; Bonciolini, S.; Gabbey, A. L.; Stuhr, R.; Poulsen, T. B. and Noël, T. Modular Synthesis of Substituted Lactams via a Deoxygenative Photochemical Alkylation–Cyclization Cascade of Secondary Amides in Flow JACS Au, 2025, 5, 4584-4592, DOI: 10.1021/jacsau.5c00884 (For the preprint version, see 10.26434/chemrxiv-2025-6qf93)
Feng, B.; Lepori, M.; Domański, M.; Tiwari, P. C.; Zhang, G.; Noël, T. and Barham, J. P. Photo-Induced N-Center Radical Catalyzed Direct Hydrogen Atom Transfer Platform for Aliphatic C–H Functionalization ChemRxiv, 2025, DOI: 10.26434/chemrxiv-2025-r2760
Noël, T. and Pieber, B. Photocatalysis and Photochemistry in Organic Synthesis Beilstein Journal of Organic Chemistry, 2025, 21, 1645-1647, DOI: 10.3762/bjoc.21.128
Djossou, J.; Aloia, A.; Capaldo, L.; Snabilié, D. D.; Regnier, M.; Schuurmans, J. H.; Monopoli, A.; Bruin, B. D. and Noël, T. Rapid Methylation of Aryl Bromides Using Air-Stable DABCO-Bis(Trimethylaluminum) via Nickel Metallaphotoredox Catalysis Angewandte Chemie International Edition, 2025, 64, e202508710, DOI: 10.1002/anie.202508710 (For the preprint version, see 10.26434/chemrxiv-2025-fv54r)
Bonciolini, S.; Pulcinella, A. and Noël, T. Tech-Enhanced Synthesis: Exploring the Synergy between Organic Chemistry and Technology Journal of the American Chemical Society, 2025, 147, 28523-28545, DOI: 10.1021/jacs.5c10303
Pilon, S.; Savino, E.; Bayley, O.; Vanzella, M.; Claros, M.; Siasiaridis, P.; Liu, J.; Lukas, F.; Damian, M.; Tseliou, V.; Intini, N.; Slattery, A.; Orduna, J.; Den Hartog, T.; Peters, R.; Gargano, A.; Mutti, F. and Noel, T. A Flexible and Affordable Self-Driving Laboratory for Automated Reaction Optimization ChemRxiv, 2025, DOI: 10.26434/chemrxiv-2025-73xqf
Tiwari, P. C.; Pulcinella, A.; Hodžić, E. and Noël, T. Late-Stage Heteroarene Alkylation via Minisci Reaction with Gaseous Alkanes Enabled by Hydrogen Atom Transfer in Flow ACS Central Science, 2025, 11, 910-917, DOI: 10.1021/acscentsci.5c00468 (For the preprint version, see 10.26434/chemrxiv-2025-wr8br)
Mesbah, A.; Wood, R.; Gao, W.; Noël, T.; Cooper, A. I.; Tilbury, D. and Qin, S. J. Sensing Connections in Automation, Control and Robotics Nature Chemical Engineering, 2025, 2, 281-284, DOI: 10.1038/s44286-025-00226-6
Regnier, M.; Vega, C.; Ioannou, D. I.; Zhang, Z. and Noël, T. Flow Electroreductive Nickel-Catalyzed Cyclopropanation of Alkenes Using Gem -Dichloroalkanes Angewandte Chemie International Edition, 2025, 64, e202500203, DOI: 10.1002/anie.202500203 (For the preprint version, see 10.26434/chemrxiv-2024-hvqtz)
Bonciolini, S.; Pulcinella, A. and Noël, T. Ethyl 2-[2-[[4-(Trifluoromethyl)Phenyl]Sulfonyl]Hydrazinylidene]Acetate Encyclopedia of Reagents for Organic Synthesis, 2025, 1-3, DOI: 10.1002/047084289X.rn02626
Chaudhuri, A.; De Groot, W. F.; Schuurmans, J. H.; Zondag, S. D.; Bianchi, A.; Kuijpers, K. P.; Broersma, R.; Delparish, A.; Dorbec, M.; Van Der Schaaf, J. and Noël, T. Scaling Up Gas–Liquid Photo-Oxidations in Flow Using Rotor-Stator Spinning Disc Reactors and a High-Intensity Light Source Organic Process Research & Development, 2025, 29, 460-471, DOI: 10.1021/acs.oprd.4c00458
Vieira, C. S. P.; Malafaia, D.; Cunha, D. R.; Leal, J. F.; António, J. P. M.; Gois, P. M. P.; Garcia-Martinez, J.; Noël, T. and Poliakoff, M. RESILIENCE by Design: Ten Principles to Guide Chemistry in a Volatile World Green Chemistry, 2025, 27, 7742-7747, DOI: 10.1039/D5GC90103K (For the preprint version, see 10.26434/chemrxiv-2025-025mt)
Schuurmans, J. H. A.; Zondag, S. D. A.; Chaudhuri, A.; Claros, M.; Van Der Schaaf, J. and Noël, T. Interaction of Light with Gas–Liquid Interfaces: Influence on Photon Absorption in Continuous-Flow Photoreactors Reaction Chemistry & Engineering, 2025, 10, 790-799, DOI: 10.1039/D4RE00540F (For the preprint version, see 10.26434/chemrxiv-2024-k0x94)
Pulcinella, A.; Bonciolini, S.; Stuhr, R.; Diprima, D.; Tran, M. T.; Johansson, M.; Von Wangelin, A. J. and Noël, T. Deoxygenative Photochemical Alkylation of Secondary Amides Enables a Streamlined Synthesis of Substituted Amines Nature Communications, 2025, 16, 948, DOI: 10.1038/s41467-025-56234-w
Pulcinella, A.; Chandra Tiwari, P.; Luridiana, A.; Yamazaki, K.; Mazzarella, D.; Sadhoe, A. K.; Alfano, A. I.; Tiekink, E. H.; Hamlin, T. A. and Noël, T. C1-4 Alkylation of Aryl Bromides with Light Alkanes Enabled by Metallaphotocatalysis in Flow Angewandte Chemie International Edition, 2025, 64, e202413846, DOI: 10.1002/anie.202413846 (For the preprint version, see 10.26434/chemrxiv-2024-7mk1c)
Lepori, M.; Ioannou, D. I.; Barham, J. P. and Noël, T. Photocatalyzed Hydrogen Atom Transfer Enables Multicomponent Olefin Oxo-Amidomethylation under Aerobic Conditions Chemical Science, 2025, 16, 22944-22951, DOI: 10.1039/D5SC06277B (For the preprint version, see 10.26434/chemrxiv-2025-whxc3)
Léonard, A. S.; Regnier, M.; Bertuletti, S.; Van Dongen, S. W.; Listro, R.; Leeman, M.; Kellogg, R. M.; Noël, T. and Noorduin, W. L. Deracemization by Coupling Electrochemically Assisted Racemization and Asymmetric Crystallization Chemical Communications, 2025, 61, 18834-18837, DOI: 10.1039/D5CC05874K
Findlay, M. T.; Lukas, F.; Rizzo, F.; Liu, J.; Martin, B.; Allmendinger, S.; Furegati, M.; Gabriel, P. and Noël, T. Graphitic Carbon Nitride/Nickel Dual Catalysis for Decarboxylative Synthesis of Unsymmetrical Ketones from Keto Acids Green Chemistry, 2025, 27, 14589-14594, DOI: 10.1039/D5GC03641K
Cotterell, N.; De Jongh, P. A. J. M.; Noël, T.; Junkers, T.; Reddy, C. M.; Anastasaki, A. and Randviir, E. Celebrating 10 Years of #RSCPoster Chemical Science, 2025, 16, 2950-2957, DOI: 10.1039/D5SC90028J
Claros, M.; Quévarec, J.; Fernández-García, S. and Noël, T. Design and Application of a Decatungstate-Based Ionic Liquid Photocatalyst for Sustainable Hydrogen Atom Transfer Reactions Green Chemistry, 2025, 27, 7660-7666, DOI: 10.1039/D5GC02160J
2024
Van Der Heide, P.; Retini, M.; Fanini, F.; Piersanti, G.; Secci, F.; Mazzarella, D.; Noël, T. and Luridiana, A. Giese-Type Alkylation of Dehydroalanine Derivatives via Silane-Mediated Alkyl Bromide Activation Beilstein Journal of Organic Chemistry, 2024, 20, 3274-3280, DOI: 10.3762/bjoc.20.271
Liu, T.; Wang, Y.; Wu, Y.; Jiang, W.; Deng, Y.; Li, Q.; Lan, C.; Zhao, Z.; Zhu, L.; Yang, D.; Noël, T. and Xie, H. Continuous Decoupled Redox Electrochemical CO2 Capture Nature Communications, 2024, 15, 10920, DOI: 10.1038/s41467-024-55334-3
Wesenberg, L. J.; Sivo, A.; Vilé, G. and Noël, T. Ni-Catalyzed Electro-Reductive Cross-Electrophile Couplings of Alkyl Amine-Derived Radical Precursors with Aryl Iodides The Journal of Organic Chemistry, 2024, 89, 16121-16125, DOI: 10.1021/acs.joc.3c00859
Spennacchio, M.; Bernús, M.; Stanić, J.; Mazzarella, D.; Colella, M.; Douglas, J. J.; Boutureira, O. and Noël, T. A Unified Flow Strategy for the Preparation and Use of Trifluoromethyl-Heteroatom Anions Science, 2024, 385, 991-996, DOI: 10.1126/science.adq2954 (For the preprint version, see 10.26434/chemrxiv-2024-3bqt6)
Mazzarella, D.; Stanić, J.; Bernús, M.; Mehdi, A. S.; Henderson, C. J.; Boutureira, O. and Noël, T. In-Flow Generation of Thionyl Fluoride (SOF2 ) Enables the Rapid and Efficient Synthesis of Acyl Fluorides from Carboxylic Acids JACS Au, 2024, 4, 2989-2994, DOI: 10.1021/jacsau.4c00318 (For the preprint version, see 10.26434/chemrxiv-2024-z41gc)
Lukas, F.; Findlay, M. T.; Fillols, M.; Templ, J.; Savino, E.; Martin, B.; Allmendinger, S.; Furegati, M. and Noël, T. Graphitic Carbon Nitride as a Photocatalyst for Decarboxylative C(Sp2 )-C(Sp3 ) Couplings via Nickel Catalysis Angewandte Chemie International Edition, 2024, 63, e202405902, DOI: 10.1002/anie.202405902 (For the preprint version, see 10.26434/chemrxiv-2024-b7kv6)
Zondag, S. D. A.; Schuurmans, J. H. A.; Chaudhuri, A.; Visser, R. P. L.; Soares, C.; Padoin, N.; Kuijpers, K. P. L.; Dorbec, M.; Van Der Schaaf, J. and Noël, T. Determining Photon Flux and Effective Optical Path Length in Intensified Flow Photoreactors Nature Chemical Engineering, 2024, 1, 462-471, DOI: 10.1038/s44286-024-00089-3 (For the preprint version, see 10.26434/chemrxiv-2024-gfk84)
Bayley, O.; Savino, E.; Slattery, A. and Noël, T. Autonomous Chemistry: Navigating Self-Driving Labs in Chemical and Material Sciences Matter, 2024, 7, 2382-2398, DOI: 10.1016/j.matt.2024.06.003
Nagornîi, D.; Raymenants, F.; Kaplaneris, N. and Noël, T. C(Sp3)–H Sulfinylation of Light Hydrocarbons with Sulfur Dioxide via Hydrogen Atom Transfer Photocatalysis in Flow Nature Communications, 2024, 15, 5246, DOI: 10.1038/s41467-024-49322-w (For the preprint version, see 10.26434/chemrxiv-2024-djx7b)
Wan, T.; Capaldo, L.; Djossou, J.; Staffa, A.; De Zwart, F. J.; De Bruin, B. and Noël, T. Rapid and Scalable Photocatalytic C(Sp2)–C(Sp3) Suzuki-Miyaura Cross-Coupling of Aryl Bromides with Alkyl Boranes Nature Communications, 2024, 15, 4028, DOI: 10.1038/s41467-024-48212-5 (For the preprint version, see 10.26434/chemrxiv-2023-4g3xz)
Kaplaneris, N.; Akdeniz, M.; Fillols, M.; Arrighi, F.; Raymenants, F.; Sanil, G.; Gryko, D. T. and Noël, T. Photocatalytic Functionalization of Dehydroalanine-Derived Peptides in Batch and Flow Angewandte Chemie International Edition, 2024, 63, e202403271, DOI: 10.1002/anie.202403271 (For the preprint version, see 10.26434/chemrxiv-2024-6fgqv)
Alcázar, J.; Anderson, E. A.; Davies, H. M. L.; Febrian, R.; Kelly, C. B.; Noël, T.; Voight, E. A.; Zarate, C. and Zysman-Colman, E. Better Together: Catalyzing Innovation in Organic Synthesis via Academic-Industrial Consortia Organic Letters, 2024, 26, 2677-2681, DOI: 10.1021/acs.orglett.4c00192
Laporte, A. A. H.; Masson, T. M.; Zondag, S. D. A. and Noël, T. Multiphasic Continuous-Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes Angewandte Chemie International Edition, 2024, 63, e202316108, DOI: 10.1002/anie.202316108
Laktsevich-Iskryk, M.; Krech, A.; Fokin, M.; Kimm, M.; Jarg, T.; Noël, T. and Ošeka, M. Telescoped Synthesis of Vicinal Diamines via Ring-Opening of Electrochemically Generated Aziridines in Flow Journal of Flow Chemistry, 2024, 14, 139-147, DOI: 10.1007/s41981-023-00296-8
Schuurmans, J. H. A.; Masson, T. M.; Zondag, S. D. A.; Buskens, P. and Noël, T. Solar-Driven Continuous CO2 Reduction to CO and CH4 Using Heterogeneous Photothermal Catalysts: Recent Progress and Remaining Challenges ChemSusChem, 2024, 17, e202301405, DOI: 10.1002/cssc.202301405
Costa E Silva, R.; Vega, C.; Regnier, M.; Capaldo, L.; Wesenberg, L.; Lowe, G.; Thiago De Oliveira, K. and Noël, T. Electrosynthesis of Aryliminophosphoranes in Continuous Flow Advanced Synthesis & Catalysis, 2024, 366, 955-960, DOI: 10.1002/adsc.202300635
Bonciolini, S.; Pulcinella, A.; Leone, M.; Schiroli, D.; Ruiz, A. L.; Sorato, A.; Dubois, M. A. J.; Gopalakrishnan, R.; Masson, G.; Della Ca', N.; Protti, S.; Fagnoni, M.; Zysman-Colman, E.; Johansson, M. and Noël, T. Metal-Free Photocatalytic Cross-Electrophile Coupling Enables C1 Homologation and Alkylation of Carboxylic Acids with Aldehydes Nature Communications, 2024, 15, 1509, DOI: 10.1038/s41467-024-45804-z (For the preprint version, see 10.26434/chemrxiv-2023-fcl2j)
Slattery, A.; Wen, Z.; Tenblad, P.; Sanjosé-Orduna, J.; Pintossi, D.; Den Hartog, T. and Noël, T. Automated Self-Optimization, Intensification, and Scale-up of Photocatalysis in Flow Science, 2024, 383, eadj1817, DOI: 10.1126/science.adj1817 (For the preprint version, see 10.26434/chemrxiv-2023-r0drq)
Schuurmans, J. H. A.; Masson, T. M.; Zondag, S. D. A.; Pilon, S.; Bragato, N.; Claros, M.; Den Hartog, T.; Sastre, F.; Van Den Ham, J.; Buskens, P.; Fiorani, G. and Noël, T. Light-Assisted Carbon Dioxide Reduction in an Automated Photoreactor System Coupled to Carbonylation Chemistry Chemical Science, 2024, 15, 19842-19850, DOI: 10.1039/D4SC06660J (For the preprint version, see 10.26434/chemrxiv-2024-sz6ng))
Regnier, M.; Vega, C.; Ioannou, D. I. and Noël, T. Enhancing Electrochemical Reactions in Organic Synthesis: The Impact of Flow Chemistry Chemical Society Reviews, 2024, 53, 10741-10760, DOI: 10.1039/D4CS00539B
Masson, T. M.; Zondag, S. D. A.; Schuurmans, J. H. A. and Noël, T. Open-Source 3D Printed Reactors for Reproducible Batch and Continuous-Flow Photon-Induced Chemistry: Design and Characterization Reaction Chemistry & Engineering, 2024, 9, 2218-2225, DOI: 10.1039/D4RE00081A
Capaldo, L.; Wan, T.; Mulder, R.; Djossou, J. and Noël, T. Visible Light-Induced Halogen-Atom Transfer by N-heterocyclic Carbene-Ligated Boryl Radicals for Diastereoselective C(Sp3 )–C(Sp2 ) Bond Formation Chemical Science, 2024, 15, 14844-14850, DOI: 10.1039/D4SC02962C
Boronin, E. N.; Svetlakova, M. M.; Vorobyov, I. I.; Malysheva, Y. B.; Polushtaytsev, Y. V.; Mensov, S. N.; Vorotyntsev, A. V.; Fedorov, A. Y.; Noël, T. and Nyuchev, A. V. Photochemical Organocatalytic Heteroarylation of Anilines and Secondary Alicyclic Amines in Continuous-Flow Reaction Chemistry & Engineering, 2024, 9, 1877-1882, DOI: 10.1039/D4RE00130C
Anwar, K.; Capaldo, L.; Wan, T.; Noël, T. and Gómez-Suárez, A. Modular Synthesis of Congested β2,2 -Amino Acids via the Merger of Photocatalysis and Oxidative Functionalisations Chemical Communications, 2024, 60, 1456-1459, DOI: 10.1039/D3CC06172H (For the preprint version, see 10.26434/chemrxiv-2023-dbc9d)
2023
Ioannou, D. I.; Capaldo, L.; Sanramat, J.; Reek, J. N. H. and Noël, T. Accelerated Electrophotocatalytic C(Sp3 )-H Heteroarylation Enabled by an Efficient Continuous-Flow Reactor** Angewandte Chemie International Edition, 2023, 62, e202315881, DOI: 10.1002/anie.202315881 (For the preprint version, see 10.26434/chemrxiv-2023-1xbvv)
Bernús, M.; Mazzarella, D.; Stanić, J.; Zhai, Z.; Yeste-Vázquez, A.; Boutureira, O.; Gargano, A. F. G.; Grossmann, T. N. and Noël, T. A Modular Flow Platform for Sulfur(VI) Fluoride Exchange Ligation of Small Molecules, Peptides and Proteins Nature Synthesis, 2023, 3, 185-191, DOI: 10.1038/s44160-023-00441-0 (For the preprint version, see 10.26434/chemrxiv-2023-gngqd)
Raymenants, F.; Masson, T. M.; Sanjosé-Orduna, J. and Noël, T. Efficient C(Sp3 )-H Carbonylation of Light and Heavy Hydrocarbons with Carbon Monoxide via Hydrogen Atom Transfer Photocatalysis in Flow** Angewandte Chemie International Edition, 2023, 62, e202308563, DOI: 10.1002/anie.202308563 (For the preprint version, see 10.26434/chemrxiv-2023-jbjh2)
Zondag, S. D.; Mazzarella, D. and Noël, T. Scale-Up of Photochemical Reactions: Transitioning from Lab Scale to Industrial Production Annual Review of Chemical and Biomolecular Engineering, 2023, 14, 283-300, DOI: 10.1146/annurev-chembioeng-101121-074313
Fanini, F.; Luridiana, A.; Mazzarella, D.; Alfano, A. I.; Van Der Heide, P.; Rincón, J. A.; García-Losada, P.; Mateos, C.; Frederick, M. O.; Nuño, M. and Noël, T. Flow Photochemical Giese Reaction via Silane-Mediated Activation of Alkyl Bromides Tetrahedron Letters, 2023, 117, 154380, DOI: 10.1016/j.tetlet.2023.154380
West, T. Lights, Flow, Transfer Nature Synthesis, 2023, 2, 198-199, DOI: 10.1038/s44160-022-00216-z
Wan, T.; Capaldo, L.; Ravelli, D.; Vitullo, W.; De Zwart, F. J.; De Bruin, B. and Noël, T. Photoinduced Halogen-Atom Transfer by N -Heterocyclic Carbene-Ligated Boryl Radicals for C(Sp3 )–C(Sp3 ) Bond Formation Journal of the American Chemical Society, 2023, 145, 991-999, DOI: 10.1021/jacs.2c10444 (For the preprint version, see 10.26434/chemrxiv-2022-8j1df)
Pulcinella, A.; Bonciolini, S.; Lukas, F.; Sorato, A. and Noël, T. Photocatalytic Alkylation of C(Sp3 )-H Bonds Using Sulfonylhydrazones** Angewandte Chemie International Edition, 2023, 62, e202215374, DOI: 10.1002/anie.202215374 (For the preprint version, see 10.26434/chemrxiv-2022-h91bz)
Capaldo, L.; Wen, Z. and Noël, T. A Field Guide to Flow Chemistry for Synthetic Organic Chemists Chemical Science, 2023, 14, 4230-4247, DOI: 10.1039/D3SC00992K
2022
Wen, Z.; Pintossi, D.; Nuño, M. and Noël, T. Membrane-Based TBADT Recovery as a Strategy to Increase the Sustainability of Continuous-Flow Photocatalytic HAT Transformations Nature Communications, 2022, 13, 6147, DOI: 10.1038/s41467-022-33821-9 (For the preprint version, see 10.26434/chemrxiv-2022-fdxzn)
Luridiana, A.; Mazzarella, D.; Capaldo, L.; Rincón, J. A.; García-Losada, P.; Mateos, C.; Frederick, M. O.; Nuño, M.; Jan Buma, W. and Noël, T. The Merger of Benzophenone HAT Photocatalysis and Silyl Radical-Induced XAT Enables Both Nickel-Catalyzed Cross-Electrophile Coupling and 1,2-Dicarbofunctionalization of Olefins ACS Catalysis, 2022, 12, 11216-11225, DOI: 10.1021/acscatal.2c03805
Bonciolini, S.; Noël, T. and Capaldo, L. Synthetic Applications of Photocatalyzed Halogen-Radical Mediated Hydrogen Atom Transfer for C-H Bond Functionalization European Journal of Organic Chemistry, 2022, 2022, e202200417, DOI: 10.1002/ejoc.202200417
Masson, T. M.; Zondag, S. D. A.; Debije, M. G. and Noël, T. Rapid and Replaceable Luminescent Coating for Silicon-Based Microreactors Enabling Energy-Efficient Solar Photochemistry ACS Sustainable Chemistry & Engineering, 2022, 10, 10712-10717, DOI: 10.1021/acssuschemeng.2c03390
Riente, P.; Fianchini, M.; Pericàs, M. A. and Noël, T. Accelerating the Photocatalytic Atom Transfer Radical Addition Reaction Induced by Bi2 O3 with Amines: Experiment and Computation ChemCatChem, 2022, 14, e202200319, DOI: 10.1002/cctc.202200319
Delparish, A.; Uslu, A.; Cao, Y.; De Groot, T.; Van Der Schaaf, J.; Noël, T. and Fernanda Neira d'Angelo, M. Boosting the Valorization of Biomass and Green Electrons to Chemical Building Blocks: A Study on the Kinetics and Mass Transfer during the Electrochemical Conversion of HMF to FDCA in a Microreactor Chemical Engineering Journal, 2022, 438, 135393, DOI: 10.1016/j.cej.2022.135393
Zondag, S. D. A.; Masson, T. M.; Debije, M. G. and Noël, T. The Development of Luminescent Solar Concentrator-Based Photomicroreactors: A Cheap Reactor Enabling Efficient Solar-Powered Photochemistry Photochemical & Photobiological Sciences, 2022, 21, 705-717, DOI: 10.1007/s43630-021-00130-x
Kooli, A.; Wesenberg, L.; Beslać, M.; Krech, A.; Lopp, M.; Noël, T. and Ošeka, M. Electrochemical Hydroxylation of Electron-Rich Arenes in Continuous Flow European Journal of Organic Chemistry, 2022, 2022, e202200011, DOI: 10.1002/ejoc.202200011
De Souza, A. A. N.; Bartolomeu, A. D. A.; Brocksom, T. J.; Noël, T. and De Oliveira, K. T. Direct Synthesis of α-Sulfenylated Ketones under Electrochemical Conditions The Journal of Organic Chemistry, 2022, 87, 5856-5865, DOI: 10.1021/acs.joc.2c00147
Capaldo, L.; Noël, T. and Ravelli, D. Photocatalytic Generation of Ligated Boryl Radicals from Tertiary Amine-Borane Complexes: An Emerging Tool in Organic Synthesis Chem Catalysis, 2022, 2, 957-966, DOI: 10.1016/j.checat.2022.03.005
Chaudhuri, A.; Zondag, S. D. A.; Schuurmans, J. H. A.; Van Der Schaaf, J. and Noël, T. Scale-Up of a Heterogeneous Photocatalytic Degradation Using a Photochemical Rotor–Stator Spinning Disk Reactor Organic Process Research & Development, 2022, 26, 1279-1288, DOI: 10.1021/acs.oprd.2c00012
Noël, T. and Zysman-Colman, E. The Promise and Pitfalls of Photocatalysis for Organic Synthesis Chem Catalysis, 2022, 2, 468-476, DOI: 10.1016/j.checat.2021.12.015
Wan, T.; Wen, Z.; Laudadio, G.; Capaldo, L.; Lammers, R.; Rincón, J. A.; García-Losada, P.; Mateos, C.; Frederick, M. O.; Broersma, R. and Noël, T. Accelerated and Scalable C(Sp3 )–H Amination via Decatungstate Photocatalysis Using a Flow Photoreactor Equipped with High-Intensity LEDs ACS Central Science, 2022, 8, 51-56, DOI: 10.1021/acscentsci.1c01109
Sanjosé-Orduna, J.; Silva, R. C.; Raymenants, F.; Reus, B.; Thaens, J.; De Oliveira, K. T. and Noël, T. Dual Role of Benzophenone Enables a Fast and Scalable C-4 Selective Alkylation of Pyridines in Flow Chemical Science, 2022, 13, 12527-12532, DOI: 10.1039/D2SC04990B
Dong, Z.; Zondag, S. D.; Schmid, M.; Wen, Z. and Noël, T. A Meso-Scale Ultrasonic Milli-Reactor Enables Gas–Liquid-Solid Photocatalytic Reactions in Flow Chemical Engineering Journal, 2022, 428, 130968, DOI: 10.1016/j.cej.2021.130968
Capaldo, L.; Bonciolini, S.; Pulcinella, A.; Nuño, M. and Noël, T. Modular Allylation of C(Sp3 )–H Bonds by Combining Decatungstate Photocatalysis and HWE Olefination in Flow Chemical Science, 2022, 13, 7325-7331, DOI: 10.1039/D2SC01581A (For the preprint version, see 10.26434/chemrxiv-2021-5vdm7)
Cao, Y.; Padoin, N.; Soares, C. and Noël, T. On the Performance of Liquid-Liquid Taylor Flow Electrochemistry in a Microreactor – A CFD Study Chemical Engineering Journal, 2022, 427, 131443, DOI: 10.1016/j.cej.2021.131443
Buglioni, L.; Raymenants, F.; Slattery, A.; Zondag, S. D. A. and Noël, T. Technological Innovations in Photochemistry for Organic Synthesis: Flow Chemistry, High-Throughput Experimentation, Scale-up, and Photoelectrochemistry Chemical Reviews, 2022, 122, 2752-2906, DOI: 10.1021/acs.chemrev.1c00332
Bajada, M. A.; Sanjosé-Orduna, J.; Di Liberto, G.; Tosoni, S.; Pacchioni, G.; Noël, T. and Vilé, G. Interfacing Single-Atom Catalysis with Continuous-Flow Organic Electrosynthesis Chemical Society Reviews, 2022, 51, 3898-3925, DOI: 10.1039/D2CS00100D
2021
Wen, Z.; Wan, T.; Vijeta, A.; Casadevall, C.; Buglioni, L.; Reisner, E. and Noël, T. Photocatalytic C-H Azolation of Arenes Using Heterogeneous Carbon Nitride in Batch and Flow ChemSusChem, 2021, 14, 5265-5270, DOI: 10.1002/cssc.202101767
Masson, T. M.; Zondag, S. D. A.; Kuijpers, K. P. L.; Cambié, D.; Debije, M. G. and Noël, T. Development of an Off-Grid Solar-Powered Autonomous Chemical Mini-Plant for Producing Fine Chemicals ChemSusChem, 2021, 14, 5417-5423, DOI: 10.1002/cssc.202102011
Buglioni, L.; Beslać, M. and Noël, T. Dehydrogenative Azolation of Arenes in a Microflow Electrochemical Reactor The Journal of Organic Chemistry, 2021, 86, 16195-16203, DOI: 10.1021/acs.joc.1c01409
Laudadio, G. and Noël, T. 1 Photochemical Transformations in Continuous-Flow Reactors Flow Chemistry – Applications, 2021, 1-30, DOI: 10.1515/9783110693690-001
Mazzarella, D.; Pulcinella, A.; Bovy, L.; Broersma, R. and Noël, T. Rapid and Direct Photocatalytic C(Sp3 )-H Acylation and Arylation in Flow Angewandte Chemie International Edition, 2021, 60, 21277-21282, DOI: 10.1002/anie.202108987
Wan, T.; Capaldo, L.; Laudadio, G.; Nyuchev, A. V.; Rincón, J. A.; García-Losada, P.; Mateos, C.; Frederick, M. O.; Nuño, M. and Noël, T. Decatungstate-Mediated C(Sp3 )–H Heteroarylation via Radical-Polar Crossover in Batch and Flow Angewandte Chemie International Edition, 2021, 60, 17893-17897, DOI: 10.1002/anie.202104682
Dong, Z.; Wen, Z.; Zhao, F.; Kuhn, S. and Noël, T. Scale-up of Micro- and Milli-Reactors: An Overview of Strategies, Design Principles and Applications Chemical Engineering Science: X, 2021, 10, 100097, DOI: 10.1016/j.cesx.2021.100097
Sambiagio, C.; Ferrari, M.; Van Beurden, K.; Ca', N. D.; Van Schijndel, J. and Noël, T. Continuous-Flow Synthesis of Pyrylium Tetrafluoroborates: Application to Synthesis of Katritzky Salts and Photoinduced Cationic RAFT Polymerization Organic Letters, 2021, 23, 2042-2047, DOI: 10.1021/acs.orglett.1c00178
Kuijpers, K. P. L.; Weggemans, W. M. A.; Verwijlen, C. J. A. and Noël, T. Flow Chemistry Experiments in the Undergraduate Teaching Laboratory: Synthesis of Diazo Dyes and Disulfides Journal of Flow Chemistry, 2021, 11, 7-12, DOI: 10.1007/s41981-020-00118-1
Cao, Y.; Soares, C.; Padoin, N. and Noël, T. Gas Bubbles Have Controversial Effects on Taylor Flow Electrochemistry Chemical Engineering Journal, 2021, 406, 126811, DOI: 10.1016/j.cej.2020.126811
Shahbazali, E.; Billaud, E. M. F.; Fard, A. S.; Meuldijk, J.; Bormans, G.; Noel, T. and Hessel, V. Photo Isomerization of Cis -cyclooctene to Trans -cyclooctene: Integration of a Micro-flow Reactor and Separation by Specific Adsorption AIChE Journal, 2021, 67, e17067, DOI: 10.1002/aic.17067
Riente, P.; Fianchini, M.; Llanes, P.; Pericàs, M. A. and Noël, T. Shedding Light on the Nature of the Catalytically Active Species in Photocatalytic Reactions Using Bi2O3 Semiconductor Nature Communications, 2021, 12, 625, DOI: 10.1038/s41467-020-20882-x
Pulcinella, A.; Mazzarella, D. and Noël, T. Homogeneous Catalytic C(Sp3 )–H Functionalization of Gaseous Alkanes Chemical Communications, 2021, 57, 9956-9967, DOI: 10.1039/D1CC04073A
Ošeka, M.; Laudadio, G.; Van Leest, N. P.; Dyga, M.; Bartolomeu, A. D. A.; Gooßen, L. J.; De Bruin, B.; De Oliveira, K. T. and Noël, T. Electrochemical Aziridination of Internal Alkenes with Primary Amines Chem, 2021, 7, 255-266, DOI: 10.1016/j.chempr.2020.12.002 (For the preprint version, see 10.26434/chemrxiv-2025-z4lnw)
Cao, Y.; Knijff, J.; Delparish, A.; d'Angelo, M. F. N. and Noёl, T. A Divergent Paired Electrochemical Process for the Conversion of Furfural Using a Divided-Cell Flow Microreactor ChemSusChem, 2021, 14, 590-594, DOI: 10.1002/cssc.202002833
2020
Chaudhuri, A.; Kuijpers, K. P.; Hendrix, R. B.; Shivaprasad, P.; Hacking, J. A.; Emanuelsson, E. A.; Noël, T. and Van Der Schaaf, J. Process Intensification of a Photochemical Oxidation Reaction Using a Rotor-Stator Spinning Disk Reactor: A Strategy for Scale Up Chemical Engineering Journal, 2020, 400, 125875, DOI: 10.1016/j.cej.2020.125875 (For the preprint version, see 10.26434/chemrxiv.11560224.v1)
Wen, Z.; Maheshwari, A.; Sambiagio, C.; Deng, Y.; Laudadio, G.; Van Aken, K.; Sun, Y.; Gemoets, H. P. L. and Noël, T. Optimization of a Decatungstate-Catalyzed C(Sp3 )–H Alkylation Using a Continuous Oscillatory Millistructured Photoreactor Organic Process Research & Development, 2020, 24, 2356-2361, DOI: 10.1021/acs.oprd.0c00235
Laudadio, G.; Deng, Y.; Van Der Wal, K.; Ravelli, D.; Nuño, M.; Fagnoni, M.; Guthrie, D.; Sun, Y. and Noël, T. C(Sp3 )–H Functionalizations of Light Hydrocarbons Using Decatungstate Photocatalysis in Flow Science, 2020, 369, 92-96, DOI: 10.1126/science.abb4688
Fernandez Rivas, D.; Boffito, D. C.; Faria-Albanese, J.; Glassey, J.; Cantin, J.; Afraz, N.; Akse, H.; Boodhoo, K. V.; Bos, R.; Chiang, Y. W.; Commenge, J. M.; Dubois, J. L.; Galli, F.; Harmsen, J.; Kalra, S.; Keil, F.; Morales-Menendez, R.; Navarro-Brull, F. J.; Noël, T.; Ogden, K.; Patience, G. S.; Reay, D.; Santos, R. M.; Smith-Schoettker, A.; Stankiewicz, A. I.; Van Den Berg, H.; Van Gerven, T.; Van Gestel, J. and Weber, R. Process Intensification Education Contributes to Sustainable Development Goals. Part 2 Education for Chemical Engineers, 2020, 32, 15-24, DOI: 10.1016/j.ece.2020.05.001
Fernandez Rivas, D.; Boffito, D. C.; Faria-Albanese, J.; Glassey, J.; Afraz, N.; Akse, H.; Boodhoo, K.; Bos, R.; Cantin, J.; (Emily) Chiang, Y. W.; Commenge, J. M.; Dubois, J. L.; Galli, F.; De Mussy, J. P. G.; Harmsen, J.; Kalra, S.; Keil, F. J.; Morales-Menendez, R.; Navarro-Brull, F. J.; Noël, T.; Ogden, K.; Patience, G. S.; Reay, D.; Santos, R. M.; Smith-Schoettker, A.; Stankiewicz, A. I.; Van Den Berg, H.; Van Gerven, T.; Van Gestel, J.; Van Der Stelt, M.; Van De Ven, M. and Weber, R. Process Intensification Education Contributes to Sustainable Development Goals. Part 1 Education for Chemical Engineers, 2020, 32, 1-14, DOI: 10.1016/j.ece.2020.04.003
Van Schijndel, J.; Molendijk, D.; Van Beurden, K.; Vermeulen, R.; Noël, T. and Meuldijk, J. Repeatable Molecularly Recyclable Semi-aromatic Polyesters Derived from Lignin Journal of Polymer Science, 2020, 58, 1655-1663, DOI: 10.1002/pol.20200088
Nyuchev, A. V.; Wan, T.; Cendón, B.; Sambiagio, C.; Struijs, J. J. C.; Ho, M.; Gulías, M.; Wang, Y. and Noël, T. Photocatalytic Trifluoromethoxylation of Arenes and Heteroarenes in Continuous-Flow Beilstein Journal of Organic Chemistry, 2020, 16, 1305-1312, DOI: 10.3762/bjoc.16.111
Sap, J. B. I.; Straathof, N. J. W.; Knauber, T.; Meyer, C. F.; Médebielle, M.; Buglioni, L.; Genicot, C.; Trabanco, A. A.; Noël, T.; Am Ende, C. W. and Gouverneur, V. Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery Journal of the American Chemical Society, 2020, 142, 9181-9187, DOI: 10.1021/jacs.0c03881
Zhang, C.; Song, Z.; Jin, C.; Nijhuis, J.; Zhou, T.; Noël, T.; Gröger, H.; Sundmacher, K.; Van Hest, J. and Hessel, V. Screening of Functional Solvent System for Automatic Aldehyde and Ketone Separation in Aldol Reaction: A Combined COSMO-RS and Experimental Approach Chemical Engineering Journal, 2020, 385, 123399, DOI: 10.1016/j.cej.2019.123399
Schönbauer, D.; Sambiagio, C.; Noël, T. and Schnürch, M. Photocatalytic Deaminative Benzylation and Alkylation of Tetrahydroisoquinolines with N -Alkylpyrydinium Salts Beilstein Journal of Organic Chemistry, 2020, 16, 809-817, DOI: 10.3762/bjoc.16.74
Govaerts, S.; Nyuchev, A. and Noel, T. Pushing the Boundaries of C–H Bond Functionalization Chemistry Using Flow Technology Journal of Flow Chemistry, 2020, 10, 13-71, DOI: 10.1007/s41981-020-00077-7
Cao, Y.; Adriaenssens, B.; De A. Bartolomeu, A.; Laudadio, G.; De Oliveira, K. T. and Noël, T. Accelerating Sulfonyl Fluoride Synthesis through Electrochemical Oxidative Coupling of Thiols and Potassium Fluoride in Flow Journal of Flow Chemistry, 2020, 10, 191-197, DOI: 10.1007/s41981-019-00070-9
Van Schijndel, J.; Molendijk, D.; Van Beurden, K.; Canalle, L. A.; Noël, T. and Meuldijk, J. Preparation of Bio-Based Styrene Alternatives and Their Free Radical Polymerization European Polymer Journal, 2020, 125, 109534, DOI: 10.1016/j.eurpolymj.2020.109534
Sambiagio, C. and Noël, T. Flow Photochemistry: Shine Some Light on Those Tubes! Trends in Chemistry, 2020, 2, 92-106, DOI: 10.1016/j.trechm.2019.09.003
Hell, S. M.; Meyer, C. F.; Laudadio, G.; Misale, A.; Willis, M. C.; Noël, T.; Trabanco, A. A. and Gouverneur, V. Silyl Radical-Mediated Activation of Sulfamoyl Chlorides Enables Direct Access to Aliphatic Sulfonamides from Alkenes Journal of the American Chemical Society, 2020, 142, 720-725, DOI: 10.1021/jacs.9b13071
De Oliveira, G. X.; Lira, J. O.; Cambié, D.; Noël, T.; Riella, H. G.; Padoin, N. and Soares, C. CFD Analysis of a Luminescent Solar Concentrator-Based Photomicroreactor (LSC-PM) with Feedforward Control Applied to the Synthesis of Chemicals under Fluctuating Light Intensity Chemical Engineering Research and Design, 2020, 153, 626-634, DOI: 10.1016/j.cherd.2019.10.047
Baker, M. J.; Gempf, K. L.; McDonald, H.; Kerr, H. E.; Hodges, C.; Anastasaki, A.; Noel, T. and Randviir, E. P. Five Years of the #RSCPoster Twitter Conference Chemical Communications, 2020, 56, 13681-13688, DOI: 10.1039/D0CC90441D
2019
Deng, Y.; Wei, X. J.; Wang, X.; Sun, Y. and Noël, T. Iron-Catalyzed Cross-Coupling of Alkynyl and Styrenyl Chlorides with Alkyl Grignard Reagents in Batch and Flow Chemistry – A European Journal, 2019, 25, 14532-14535, DOI: 10.1002/chem.201904480
Noël, T.; Cao, Y. and Laudadio, G. The Fundamentals Behind the Use of Flow Reactors in Electrochemistry Accounts of Chemical Research, 2019, 52, 2858-2869, DOI: 10.1021/acs.accounts.9b00412
Cambié, D.; Dobbelaar, J.; Riente, P.; Vanderspikken, J.; Shen, C.; Seeberger, P. H.; Gilmore, K.; Debije, M. G. and Noël, T. Energy-Efficient Solar Photochemistry with Luminescent Solar Concentrator Based Photomicroreactors Angewandte Chemie International Edition, 2019, 58, 14374-14378, DOI: 10.1002/anie.201908553
Wei, X. J.; Abdiaj, I.; Sambiagio, C.; Li, C.; Zysman-Colman, E.; Alcázar, J. and Noël, T. Visible-Light-Promoted Iron-Catalyzed C(Sp2 )–C(Sp3 ) Kumada Cross-Coupling in Flow Angewandte Chemie International Edition, 2019, 58, 13030-13034, DOI: 10.1002/anie.201906462
Bartolomeu, A. D. A.; Silva, R. C.; Brocksom, T. J.; Noël, T. and De Oliveira, K. T. Photoarylation of Pyridines Using Aryldiazonium Salts and Visible Light: An EDA Approach The Journal of Organic Chemistry, 2019, 84, 10459-10471, DOI: 10.1021/acs.joc.9b01879
Laudadio, G.; Bartolomeu, A. D. A.; Verwijlen, L. M. H. M.; Cao, Y.; De Oliveira, K. T. and Noël, T. Sulfonyl Fluoride Synthesis through Electrochemical Oxidative Coupling of Thiols and Potassium Fluoride Journal of the American Chemical Society, 2019, 141, 11832-11836, DOI: 10.1021/jacs.9b06126
Laudadio, G.; Barmpoutsis, E.; Schotten, C.; Struik, L.; Govaerts, S.; Browne, D. L. and Noël, T. Sulfonamide Synthesis through Electrochemical Oxidative Coupling of Amines and Thiols Journal of the American Chemical Society, 2019, 141, 5664-5668, DOI: 10.1021/jacs.9b02266
Cao, Y. and Noël, T. Efficient Electrocatalytic Reduction of Furfural to Furfuryl Alcohol in a Microchannel Flow Reactor Organic Process Research & Development, 2019, 23, 403-408, DOI: 10.1021/acs.oprd.8b00428
Bottecchia, C.; Martín, R.; Abdiaj, I.; Crovini, E.; Alcazar, J.; Orduna, J.; Blesa, M. J.; Carrillo, J. R.; Prieto, P. and Noël, T. De Novo Design of Organic Photocatalysts: Bithiophene Derivatives for the Visible-light Induced C-H Functionalization of Heteroarenes Advanced Synthesis & Catalysis, 2019, 361, 945-950, DOI: 10.1002/adsc.201801571
Riente, P. and Noël, T. Application of Metal Oxide Semiconductors in Light-Driven Organic Transformations Catalysis Science & Technology, 2019, 9, 5186-5232, DOI: 10.1039/C9CY01170F
Bottecchia, C. and Noël, T. Photocatalytic Modification of Amino Acids, Peptides, and Proteins Chemistry – A European Journal, 2019, 25, 26-42, DOI: 10.1002/chem.201803074
2018
Laudadio, G.; De Smet, W.; Struik, L.; Cao, Y. and Noël, T. Design and Application of a Modular and Scalable Electrochemical Flow Microreactor Journal of Flow Chemistry, 2018, 8, 157-165, DOI: 10.1007/s41981-018-0024-3
Cambié, D. and Noël, T. Solar Photochemistry in Flow Topics in Current Chemistry, 2018, 376, 45, DOI: 10.1007/s41061-018-0223-2
Escribà-Gelonch, M.; Halpin, A.; Noël, T. and Hessel, V. Laser-Mediated Photo-High-p,T Intensification of Vitamin D3 Synthesis in Continuous Flow ChemPhotoChem, 2018, 2, 922-930, DOI: 10.1002/cptc.201800102
Booker-Milburn, K. I. and Noël, T. Flow Photochemistry ChemPhotoChem, 2018, 2, 830-830, DOI: 10.1002/cptc.201800184
Wei, X. J. and Noël, T. Visible-Light Photocatalytic Difluoroalkylation-Induced 1, 2-Heteroarene Migration of Allylic Alcohols in Batch and Flow The Journal of Organic Chemistry, 2018, 83, 11377-11384, DOI: 10.1021/acs.joc.8b01624
Casnati, A.; Gemoets, H. P. L.; Motti, E.; Della Ca', N. and Noël, T. Homogeneous and Gas–Liquid Catellani-Type Reaction Enabled by Continuous-Flow Chemistry Chemistry – A European Journal, 2018, 24, 14079-14083, DOI: 10.1002/chem.201803909
Kuijpers, K. P. L.; Bottecchia, C.; Cambié, D.; Drummen, K.; König, N. J. and Noël, T. A Fully Automated Continuous-Flow Platform for Fluorescence Quenching Studies and Stern–Volmer Analysis Angewandte Chemie International Edition, 2018, 57, 11278-11282, DOI: 10.1002/anie.201805632
Stephenson, C.; Yoon, T. and MacMillan, D. W. C. Visible Light Photocatalysis in Organic Chemistry 2018, DOI: 10.1002/9783527674145
Laudadio, G.; Govaerts, S.; Wang, Y.; Ravelli, D.; Koolman, H. F.; Fagnoni, M.; Djuric, S. W. and Noël, T. Selective C(Sp3 )-H Aerobic Oxidation Enabled by Decatungstate Photocatalysis in Flow Angewandte Chemie International Edition, 2018, 57, 4078-4082, DOI: 10.1002/anie.201800818
Van Schie, M. M. C. H.; Pedroso De Almeida, T.; Laudadio, G.; Tieves, F.; Fernández-Fueyo, E.; Noël, T.; Arends, I. W. C. E. and Hollmann, F. Biocatalytic Synthesis of the Green Note Trans -2-Hexenal in a Continuous-Flow Microreactor Beilstein Journal of Organic Chemistry, 2018, 14, 697-703, DOI: 10.3762/bjoc.14.58
Escribà-Gelonch, M.; Noël, T. and Hessel, V. Microflow High-p,T Intensification of Vitamin D3 Synthesis Using an Ultraviolet Lamp Organic Process Research & Development, 2018, 22, 147-155, DOI: 10.1021/acs.oprd.7b00318
Escribà-Gelonch, M.; Hessel, V.; Maier, M. C.; Noël, T.; Neira d'Angelo, M. F. and Gruber-Woelfler, H. Continuous-Flow In-Line Solvent-Swap Crystallization of Vitamin D3 Organic Process Research & Development, 2018, 22, 178-189, DOI: 10.1021/acs.oprd.7b00351
Zhao, F.; Cambié, D.; Janse, J.; Wieland, E. W.; Kuijpers, K. P. L.; Hessel, V.; Debije, M. G. and Noël, T. Scale-up of a Luminescent Solar Concentrator-Based Photomicroreactor via Numbering-up ACS Sustainable Chemistry & Engineering, 2018, 6, 422-429, DOI: 10.1021/acssuschemeng.7b02687
Zhao, F.; Cambié, D.; Hessel, V.; Debije, M. G. and Noël, T. Real-Time Reaction Control for Solar Production of Chemicals under Fluctuating Irradiance Green Chemistry, 2018, 20, 2459-2464, DOI: 10.1039/C8GC00613J
Flow Chemistry in Organic Synthesis 2018, b-006-161272, DOI: 10.1055/b-006-161272
2017
Laudadio, G.; Gemoets, H. P. L.; Hessel, V. and Noël, T. Flow Synthesis of Diaryliodonium Triflates The Journal of Organic Chemistry, 2017, 82, 11735-11741, DOI: 10.1021/acs.joc.7b01346
Gruber-Woelfler, H.; Escribà-Gelonch, M.; Noël, T.; Maier, M. C. and Hessel, V. Effect of Acetonitrile-Based Crystallization Conditions on the Crystal Quality of Vitamin D3 Chemical Engineering & Technology, 2017, 40, 2016-2024, DOI: 10.1002/ceat.201700080
Abdiaj, I.; Bottecchia, C.; Alcazar, J. and Noёl, T. Visible-Light-Induced Trifluoromethylation of Highly Functionalized Arenes and Heteroarenes in Continuous Flow Synthesis, 2017, 49, 4978-4985, DOI: 10.1055/s-0036-1588527
Wei, X. J.; Boon, W.; Hessel, V. and Noël, T. Visible-Light Photocatalytic Decarboxylation of α,β-Unsaturated Carboxylic Acids: Facile Access to Stereoselective Difluoromethylated Styrenes in Batch and Flow ACS Catalysis, 2017, 7, 7136-7140, DOI: 10.1021/acscatal.7b03019
Bottecchia, C.; Rubens, M.; Gunnoo, S. B.; Hessel, V.; Madder, A. and Noël, T. Visible-Light-Mediated Selective Arylation of Cysteine in Batch and Flow Angewandte Chemie International Edition, 2017, 56, 12702-12707, DOI: 10.1002/anie.201706700
Noël, T. A Personal Perspective on the Future of Flow Photochemistry Journal of Flow Chemistry, 2017, 7, 87-93, DOI: 10.1556/1846.2017.00022
Sharma, U. K.; Gemoets, H. P. L.; Schröder, F.; Noël, T. and Van Der Eycken, E. V. Merger of Visible-Light Photoredox Catalysis and C–H Activation for the Room-Temperature C-2 Acylation of Indoles in Batch and Flow ACS Catalysis, 2017, 7, 3818-3823, DOI: 10.1021/acscatal.7b00840
Gemoets, H. P. L.; Laudadio, G.; Verstraete, K.; Hessel, V. and Noël, T. A Modular Flow Design for the Meta -Selective C-H Arylation of Anilines Angewandte Chemie International Edition, 2017, 56, 7161-7165, DOI: 10.1002/anie.201703369
Shang, M.; Noël, T.; Su, Y. and Hessel, V. Kinetic Study of Hydrogen Peroxide Decomposition at High Temperatures and Concentrations in Two Capillary Microreactors AIChE Journal, 2017, 63, 689-697, DOI: 10.1002/aic.15385
Laudadio, G. and Noël, T. Flow Chemistry Perspective for C H Bond Functionalization Strategies for Palladium-Catalyzed Non-Directed and Directed C-H Bond Functionalization, 2017, 275-288, DOI: 10.1016/B978-0-12-805254-9.00007-4
Laudadio, G.; Straathof, N. J. W.; Lanting, M. D.; Knoops, B.; Hessel, V. and Noël, T. An Environmentally Benign and Selective Electrochemical Oxidation of Sulfides and Thiols in a Continuous-Flow Microreactor Green Chemistry, 2017, 19, 4061-4066, DOI: 10.1039/C7GC01973D
Kuijpers, K. P. L.; Van Dijk, M. A. H.; Rumeur, Q. G.; Hessel, V.; Su, Y. and Noël, T. A Sensitivity Analysis of a Numbered-up Photomicroreactor System Reaction Chemistry & Engineering, 2017, 2, 109-115, DOI: 10.1039/C7RE00024C
Kockmann, N.; Thenée, P.; Fleischer-Trebes, C.; Laudadio, G. and Noël, T. Safety Assessment in Development and Operation of Modular Continuous-Flow Processes Reaction Chemistry & Engineering, 2017, 2, 258-280, DOI: 10.1039/C7RE00021A
Gemoets, H. P. L.; Kalvet, I.; Nyuchev, A. V.; Erdmann, N.; Hessel, V.; Schoenebeck, F. and Noël, T. Mild and Selective Base-Free C–H Arylation of Heteroarenes: Experiment and Computation Chemical Science, 2017, 8, 1046-1055, DOI: 10.1039/C6SC02595A
Deng, Y.; Wei, X. J.; Wang, H.; Sun, Y.; Noël, T. and Wang, X. Disulfide-Catalyzed Visible-Light-Mediated Oxidative Cleavage of C=C Bonds and Evidence of an Olefin–Disulfide Charge-Transfer Complex Angewandte Chemie International Edition, 2017, 56, 832-836, DOI: 10.1002/anie.201607948
Cambié, D.; Zhao, F.; Hessel, V.; Debije, M. G. and Noël, T. A Leaf-Inspired Luminescent Solar Concentrator for Energy-Efficient Continuous-Flow Photochemistry Angewandte Chemie International Edition, 2017, 56, 1050-1054, DOI: 10.1002/anie.201611101
Cambié, D.; Zhao, F.; Hessel, V.; Debije, M. G. and Noël, T. Every Photon Counts: Understanding and Optimizing Photon Paths in Luminescent Solar Concentrator-Based Photomicroreactors (LSC-PMs) Reaction Chemistry & Engineering, 2017, 2, 561-566, DOI: 10.1039/C7RE00077D
Billaud, E. M. F.; Shahbazali, E.; Ahamed, M.; Cleeren, F.; Noël, T.; Koole, M.; Verbruggen, A.; Hessel, V. and Bormans, G. Micro-Flow Photosynthesis of New Dienophiles for Inverse-Electron-Demand Diels–Alder Reactions. Potential Applications for Pretargeted in Vivo PET Imaging Chemical Science, 2017, 8, 1251-1258, DOI: 10.1039/C6SC02933G
Adouama, C.; Keyrouz, R.; Pilet, G.; Monnereau, C.; Gueyrard, D.; Noël, T. and Médebielle, M. Access to Cyclic Gem-Difluoroacyl Scaffolds via Electrochemical and Visible Light Photocatalytic Radical Tandem Cyclization of Heteroaryl Chlorodifluoromethyl Ketones Chemical Communications, 2017, 53, 5653-5656, DOI: 10.1039/C7CC02979A
2016
Straathof, N. J. W.; Cramer, S. E.; Hessel, V. and Noël, T. Practical Photocatalytic Trifluoromethylation and Hydrotrifluoromethylation of Styrenes in Batch and Flow Angewandte Chemie International Edition, 2016, 55, 15549-15553, DOI: 10.1002/anie.201608297
Cambié, D.; Bottecchia, C.; Straathof, N. J. W.; Hessel, V. and Noël, T. Applications of Continuous-Flow Photochemistry in Organic Synthesis, Material Science, and Water Treatment Chemical Reviews, 2016, 116, 10276-10341, DOI: 10.1021/acs.chemrev.5b00707
Su, Y.; Kuijpers, K. P. L.; König, N.; Shang, M.; Hessel, V. and Noël, T. A Mechanistic Investigation of the Visible-Light Photocatalytic Trifluoromethylation of Heterocycles Using CF3 I in Flow Chemistry – A European Journal, 2016, 22, 12295-12300, DOI: 10.1002/chem.201602596
Gemoets, H. P. L.; Hessel, V. and Noël, T. Reactor Concepts for Aerobic Liquid Phase Oxidation: Microreactors and Tube Reactors Liquid Phase Aerobic Oxidation Catalysis: Industrial Applications and Academic Perspectives, 2016, 397-419, DOI: 10.1002/9783527690121.ch23
Bottecchia, C.; Wei, X. J.; Kuijpers, K. P. L.; Hessel, V. and Noël, T. Visible Light-Induced Trifluoromethylation and Perfluoroalkylation of Cysteine Residues in Batch and Continuous Flow The Journal of Organic Chemistry, 2016, 81, 7301-7307, DOI: 10.1021/acs.joc.6b01031
Shahbazali, E.; Noël, T. and Hessel, V. Photo-Claisen Rearrangement of Allyl Phenyl Ether in Microflow: Influence of Phenyl Core Substituents and Vision on Orthogonality Journal of Flow Chemistry, 2016, 6, 252-259, DOI: 10.1556/1846.2016.00029
Bottecchia, C.; Erdmann, N.; Tijssen, P. M. A.; Milroy, L. G.; Brunsveld, L.; Hessel, V. and Noël, T. Batch and Flow Synthesis of Disulfides by Visible-Light-Induced TiO2 Photocatalysis ChemSusChem, 2016, 9, 1781-1785, DOI: 10.1002/cssc.201600602
Erdmann, N.; Su, Y.; Bosmans, B.; Hessel, V. and Noël, T. Palladium-Catalyzed Aerobic Oxidative Coupling of o -Xylene in Flow: A Safe and Scalable Protocol for Cross-Dehydrogenative Coupling Organic Process Research & Development, 2016, 20, 831-835, DOI: 10.1021/acs.oprd.6b00044
Shang, M.; Noël, T.; Su, Y. and Hessel, V. High Pressure Direct Synthesis of Adipic Acid from Cyclohexene and Hydrogen Peroxide via Capillary Microreactors Industrial & Engineering Chemistry Research, 2016, 55, 2669-2676, DOI: 10.1021/acs.iecr.5b04813
Borukhova, S.; Noël, T. and Hessel, V. Hydrogen Chloride Gas in Solvent-Free Continuous Conversion of Alcohols to Chlorides in Microflow Organic Process Research & Development, 2016, 20, 568-573, DOI: 10.1021/acs.oprd.6b00014
Vural Gürsel, I.; Kurt, S. K.; Aalders, J.; Wang, Q.; Noël, T.; Nigam, K. D.; Kockmann, N. and Hessel, V. Utilization of Milli-Scale Coiled Flow Inverter in Combination with Phase Separator for Continuous Flow Liquid–Liquid Extraction Processes Chemical Engineering Journal, 2016, 283, 855-868, DOI: 10.1016/j.cej.2015.08.028
Su, Y.; Kuijpers, K.; Hessel, V. and Noël, T. A Convenient Numbering-up Strategy for the Scale-up of Gas–Liquid Photoredox Catalysis in Flow Reaction Chemistry & Engineering, 2016, 1, 73-81, DOI: 10.1039/C5RE00021A
Straathof, N. J. W.; Su, Y.; Hessel, V. and Noël, T. Accelerated Gas-Liquid Visible Light Photoredox Catalysis with Continuous-Flow Photochemical Microreactors Nature Protocols, 2016, 11, 10-21, DOI: 10.1038/nprot.2015.113
Stouten, S. C.; Noël, T.; Wang, Q.; Beller, M. and Hessel, V. Continuous Ruthenium-Catalyzed Methoxycarbonylation with Supercritical Carbon Dioxide Catalysis Science & Technology, 2016, 6, 4712-4717, DOI: 10.1039/C5CY01883H
Gemoets, H. P. L.; Su, Y.; Shang, M.; Hessel, V.; Luque, R. and Noël, T. Liquid Phase Oxidation Chemistry in Continuous-Flow Microreactors Chemical Society Reviews, 2016, 45, 83-117, DOI: 10.1039/C5CS00447K
Borukhova, S.; Noël, T. and Hessel, V. Continuous-Flow Multistep Synthesis of Cinnarizine, Cyclizine, and a Buclizine Derivative from Bulk Alcohols ChemSusChem, 2016, 9, 67-74, DOI: 10.1002/cssc.201501367
Borukhova, S.; Noël, T.; Metten, B.; De Vos, E. and Hessel, V. From Alcohol to 1,2,3-Triazole via a Multi-Step Continuous-Flow Synthesis of a Rufinamide Precursor Green Chemistry, 2016, 18, 4947-4953, DOI: 10.1039/C6GC01133K
2015
Shahbazali, E.; Spapens, M.; Kobayashi, H.; Ookawara, S.; Noël, T. and Hessel, V. Connected Nucleophilic Substitution-Claisen Rearrangement in Flow – Analysis for Kilo-Lab Process Solutions with Orthogonality Chemical Engineering Journal, 2015, 281, 144-154, DOI: 10.1016/j.cej.2015.06.020
Stouten, S.; Noël, T.; Wang, Q. and Hessel, V. Supported Liquid Phase Catalyst Coating in Micro Flow Mizoroki–Heck Reaction Chemical Engineering Journal, 2015, 279, 143-148, DOI: 10.1016/j.cej.2015.05.026
Su, Y.; Talla, A.; Hessel, V. and Noël, T. Controlled Photocatalytic Aerobic Oxidation of Thiols to Disulfides in an Energy-Efficient Photomicroreactor Chemical Engineering & Technology, 2015, 38, 1733-1742, DOI: 10.1002/ceat.201500376
Schröder, F.; Erdmann, N.; Noël, T.; Luque, R. and Van der Eycken, E. V. Leaching-Free Supported Gold Nanoparticles Catalyzing Cycloisomerizations under Microflow Conditions Advanced Synthesis & Catalysis, 2015, 357, 3141-3147, DOI: 10.1002/adsc.201500628
Talla, A.; Driessen, B.; Straathof, N. J. W.; Milroy, L. G.; Brunsveld, L.; Hessel, V. and Noël, T. Metal-Free Photocatalytic Aerobic Oxidation of Thiols to Disulfides in Batch and Continuous-Flow Advanced Synthesis & Catalysis, 2015, 357, 2180-2186, DOI: 10.1002/adsc.201401010
Su, Y.; Hessel, V. and Noël, T. A Compact Photomicroreactor Design for Kinetic Studies of Gas-liquid Photocatalytic Transformations AIChE Journal, 2015, 61, 2215-2227, DOI: 10.1002/aic.14813
Vural Gürsel, I.; Aldiansyah, F.; Wang, Q.; Noël, T. and Hessel, V. Continuous Metal Scavenging and Coupling to One-Pot Copper-Catalyzed Azide-Alkyne Cycloaddition Click Reaction in Flow Chemical Engineering Journal, 2015, 270, 468-475, DOI: 10.1016/j.cej.2015.02.035
Borukhova, S.; Seeger, A. D.; Noël, T.; Wang, Q.; Busch, M. and Hessel, V. Pressure-Accelerated Azide–Alkyne Cycloaddition: Micro Capillary versus Autoclave Reactor Performance ChemSusChem, 2015, 8, 504-512, DOI: 10.1002/cssc.201403034
Vural Gürsel, I.; Noël, T.; Wang, Q. and Hessel, V. Separation/Recycling Methods for Homogeneous Transition Metal Catalysts in Continuous Flow Green Chemistry, 2015, 17, 2012-2026, DOI: 10.1039/C4GC02160F
Shang, M.; Noël, T.; Wang, Q.; Su, Y.; Miyabayashi, K.; Hessel, V. and Hasebe, S. 2- and 3-Stage Temperature Ramping for the Direct Synthesis of Adipic Acid in Micro-Flow Packed-Bed Reactors Chemical Engineering Journal, 2015, 260, 454-462, DOI: 10.1016/j.cej.2014.08.061
Schröder, F.; Ojeda, M.; Erdmann, N.; Jacobs, J.; Luque, R.; Noël, T.; Van Meervelt, L.; Van Der Eycken, J. and Van Der Eycken, E. V. Supported Gold Nanoparticles as Efficient and Reusable Heterogeneous Catalyst for Cycloisomerization Reactions Green Chemistry, 2015, 17, 3314-3318, DOI: 10.1039/C5GC00430F
Noël, T.; Su, Y. and Hessel, V. Beyond Organometallic Flow Chemistry: The Principles Behind the Use of Continuous-Flow Reactors for Synthesis Organometallic Flow Chemistry, 2015, 57, 1-41, DOI: 10.1007/3418_2015_152
Habraken, E. R. M.; Haspeslagh, P.; Vliegen, M. and Noël, T. Iridium(I)-Catalyzed Ortho-Directed Hydrogen Isotope Exchange in Continuous-Flow Reactors Journal of Flow Chemistry, 2015, 5, 2-5, DOI: 10.1556/JFC-D-14-00033
2014
Hessel, V.; Shahbazali, E.; Noël, T. and Zelentsov, S. Claisen-Umlagerung Im Rühr- Und Durchflussbetrieb: Verständnis Des Mechanismus Und Steuerung Der Einflussgrößen Chemie Ingenieur Technik, 2014, 86, 2160-2179, DOI: 10.1002/cite.201400125
Hessel, V.; Shahbazali, E.; Noël, T. and Zelentsov, S. The Claisen Rearrangement – Part 2: Impact Factor Analysis of the Claisen Rearrangement, in Batch and in Flow ChemBioEng Reviews, 2014, 1, 244-261, DOI: 10.1002/cben.201400022
Gemoets, H. P. L.; Hessel, V. and Noël, T. Aerobic C–H Olefination of Indoles via a Cross-Dehydrogenative Coupling in Continuous Flow Organic Letters, 2014, 16, 5800-5803, DOI: 10.1021/ol502910e
Denčić, I.; Ott, D.; Kralisch, D.; Noël, T.; Meuldijk, J.; De Croon, M.; Hessel, V.; Laribi, Y. and Perrichon, P. Eco-Efficiency Analysis for Intensified Production of an Active Pharmaceutical Ingredient: A Case Study Organic Process Research & Development, 2014, 18, 1326-1338, DOI: 10.1021/op5000573
Zelentsov, S.; Hessel, V.; Shahbazali, E. and Noël, T. The Claisen Rearrangement – Part 1: Mechanisms and Transition States, Revisited with Quantum Mechanical Calculations and Ultrashort Pulse Spectroscopy ChemBioEng Reviews, 2014, 1, 230-240, DOI: 10.1002/cben.201400021
Stouten, S.; Noël, T.; Wang, Q. and Hessel, V. Catalyst Retention in Continuous Flow with Supercritical Carbon Dioxide Chemical Engineering and Processing: Process Intensification, 2014, 83, 26-32, DOI: 10.1016/j.cep.2014.03.017
Su, Y.; Straathof, N. J. W.; Hessel, V. and Noël, T. Photochemical Transformations Accelerated in Continuous-Flow Reactors: Basic Concepts and Applications Chemistry – A European Journal, 2014, 20, 10562-10589, DOI: 10.1002/chem.201400283
Straathof, N. J. W.; Tegelbeckers, B. J. P.; Hessel, V.; Wang, X. and Noël, T. A Mild and Fast Photocatalytic Trifluoromethylation of Thiols in Batch and Continuous-Flow Chem. Sci., 2014, 5, 4768-4773, DOI: 10.1039/C4SC01982B
I.V., G.; Q., W.; T., N.; G., K.; V., H. and A.C., V. V. Heat-Integrated Novel Process of Liquid Fuel Production from Bioresources Process Simulation and Costing Study Chemical Engineering Transactions, 2014, 39, 931-936, DOI: 10.3303/CET1439156
Straathof, N. J. W.; Gemoets, H. P. L.; Wang, X.; Schouten, J. C.; Hessel, V. and Noël, T. Rapid Trifluoromethylation and Perfluoroalkylation of Five-Membered Heterocycles by Photoredox Catalysis in Continuous Flow ChemSusChem, 2014, 7, 1612-1617, DOI: 10.1002/cssc.201301282
Noël, T. Micro Flow Chemistry: New Possibilities for Synthetic Chemists Discovering the Future of Molecular Sciences, 2014, 137-164, DOI: 10.1002/9783527673223.ch6
Baraldi, P. T.; Noël, T.; Wang, Q. and Hessel, V. The Accelerated Preparation of 1,4-Dihydropyridines Using Microflow Reactors Tetrahedron Letters, 2014, 55, 2090-2092, DOI: 10.1016/j.tetlet.2014.02.041
Shahbazali, E.; Hessel, V.; Noël, T. and Wang, Q. Metallic Nanoparticles Made in Flow and Their Catalytic Applications in Organic Synthesis Nanotechnology Reviews, 2014, 3, 65-86, DOI: 10.1515/ntrev-2013-0017
Straathof, N. J. W.; Van Osch, D. J. G. P.; Schouten, A.; Wang, X.; Schouten, J. C.; Hessel, V. and Noël, T. Visible Light Photocatalytic Metal-Free Perfluoroalkylation of Heteroarenes in Continuous Flow Journal of Flow Chemistry, 2014, 4, 12-17, DOI: 10.1556/JFC-D-13-00032
Noël, T. and Hessel, V. Micro Process Technology, 3. Applications Ullmann's Encyclopedia of Industrial Chemistry, 2014, 1-42, DOI: 10.1002/14356007.o16_o02
Noël, T. and Hessel, V. CHAPTER 13. Cross-Coupling Chemistry in Continuous Flow Catalysis Series, 2014, 610-644, DOI: 10.1039/9781782620259-00610
Hessel, V.; Tibhe, J.; Noël, T. and Wang, Q. Biotechnical Micro-Flow Processing at the EDGE – Lessons to Be Learnt for a Young Discipline Chemical and Biochemical Engineering Quarterly Journal, 2014, 28, 167-188, DOI: 10.15255/CABEQ.2014.1939
2013
Borukhova, S.; Noël, T.; Metten, B.; de Vos, E. and Hessel, V. Solvent- and Catalyst-Free Huisgen Cycloaddition to Rufinamide in Flow with a Greener, Less Expensive Dipolarophile ChemSusChem, 2013, 6, 2220-2225, DOI: 10.1002/cssc.201300684
Tibhe, J. D.; Fu, H.; Noël, T.; Wang, Q.; Meuldijk, J. and Hessel, V. Flow Synthesis of Phenylserine Using Threonine Aldolase Immobilized on Eupergit Support Beilstein Journal of Organic Chemistry, 2013, 9, 2168-2179, DOI: 10.3762/bjoc.9.254
I., V. G.; Q., W.; T., N. and V., H. Implementation of Heat Integration for Efficient Process Design of Direct Adipic Acid Synthesis in Flow Chemical Engineering Transactions, 2013, 35, 775-780, DOI: 10.3303/CET1335129
Noël, T. and Hessel, V. Chemical Intensification in Flow Chemistry through Harsh Reaction Conditions and New Reaction Design Microreactors in Preparative Chemistry, 2013, 273-295, DOI: 10.1002/9783527652891.ch11
Denčić, I.; De Vaan, S.; Noël, T.; Meuldijk, J.; De Croon, M. and Hessel, V. Lipase-Based Biocatalytic Flow Process in a Packed-Bed Microreactor Industrial & Engineering Chemistry Research, 2013, 52, 10951-10960, DOI: 10.1021/ie400348f
Wang, X.; Cuny, G. D. and Noël, T. A Mild, One-Pot Stadler–Ziegler Synthesis of Arylsulfides Facilitated by Photoredox Catalysis in Batch and Continuous-Flow Angewandte Chemie International Edition, 2013, 52, 7860-7864, DOI: 10.1002/anie.201303483
Denčić, I.; Noël, T.; Meuldijk, J.; De Croon, M. and Hessel, V. Micro Reaction Technology for Valorization of Biomolecules Using Enzymes and Metal Catalysts Engineering in Life Sciences, 2013, 13, 326-343, DOI: 10.1002/elsc.201200149
Vural-Gürsel, I.; Wang, Q.; Noël, T.; Hessel, V. and Tinge, J. T. Improving Energy Efficiency of Process of Direct Adipic Acid Synthesis in Flow Using Pinch Analysis Industrial & Engineering Chemistry Research, 2013, 52, 7827-7835, DOI: 10.1021/ie4002052
Shang, M.; Noël, T.; Wang, Q. and Hessel, V. Packed-Bed Microreactor for Continuous-Flow Adipic Acid Synthesis from Cyclohexene and Hydrogen Peroxide Chemical Engineering & Technology, 2013, 36, 1001-1009, DOI: 10.1002/ceat.201200703
Hessel, V.; Kralisch, D.; Kockmann, N.; Noël, T. and Wang, Q. Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry ChemSusChem, 2013, 6, 746-789, DOI: 10.1002/cssc.201200766
Stouten, S. C.; Wang, Q.; Noël, T. and Hessel, V. A Supported Aqueous Phase Catalyst Coating in Micro Flow Mizoroki–Heck Reaction Tetrahedron Letters, 2013, 54, 2194-2198, DOI: 10.1016/j.tetlet.2013.02.064
Kobayashi, H.; Driessen, B.; Van Osch, D. J.; Talla, A.; Ookawara, S.; Noël, T. and Hessel, V. The Impact of Novel Process Windows on the Claisen Rearrangement Tetrahedron, 2013, 69, 2885-2890, DOI: 10.1016/j.tet.2013.02.038
Noël, T. and Hessel, V. Membrane Microreactors: Gas–Liquid Reactions Made Easy ChemSusChem, 2013, 6, 405-407, DOI: 10.1002/cssc.201200913
Noël, T. and Van Der Eycken, J. Ferrocene-Derived P,N Ligands: Synthesis and Application in Enantioselective Catalysis gps, 2013, 2, 297-309, DOI: 10.1515/gps-2013-0036
Stouten, S. C.; Noël, T.; Wang, Q. and Hessel, V. A View Through Novel Process Windows Australian Journal of Chemistry, 2013, 66, 121-130, DOI: 10.1071/CH12465
2012
Cortese, B.; Noel, T.; De Croon, M. H. J. M.; Schulze, S.; Klemm, E. and Hessel, V. Modeling of Anionic Polymerization in Flow With Coupled Variations of Concentration, Viscosity, and Diffusivity Macromolecular Reaction Engineering, 2012, 6, 507-515, DOI: 10.1002/mren.201200027
Hessel, V. and Noël, T. Micro Process Technology, 2. Processing Ullmann's Encyclopedia of Industrial Chemistry, 2012, DOI: 10.1002/14356007.b16_b37.pub2
Hessel, V. and Noël, T. Micro Process Technology, 1. Introduction Ullmann's Encyclopedia of Industrial Chemistry, 2012, DOI: 10.1002/14356007.q16_q01
Fu, H.; Dencic, I.; Tibhe, J.; Sanchez Pedraza, C.; Wang, Q.; Noel, T.; Meuldijk, J.; De Croon, M.; Hessel, V.; Weizenmann, N.; Oeser, T.; Kinkeade, T.; Hyatt, D.; Van Roy, S.; Dejonghe, W. and Diels, L. Threonine Aldolase Immobilization on Different Supports for Engineering of Productive, Cost-Efficient Enzymatic Microreactors Chemical Engineering Journal, 2012, 207--208, 564-576, DOI: 10.1016/j.cej.2012.07.017
I., V. G.; Q., W.; T., N. and V., H. Process-Design Intensification Direct Synthesis of Adipic Acid in Flow Chemical Engineering Transactions, 2012, 29, 565-570, DOI: 10.3303/CET1229095
Varas, A. C.; Noël, T.; Wang, Q. and Hessel, V. Copper(I)-Catalyzed Azide–Alkyne Cycloadditions in Microflow: Catalyst Activity, High-T Operation, and an Integrated Continuous Copper Scavenging Unit ChemSusChem, 2012, 5, 1703-1707, DOI: 10.1002/cssc.201200323
Hessel, V.; Vural Gürsel, I.; Wang, Q.; Noël, T. and Lang, J. Potential Analysis of Smart Flow Processing and Micro Process Technology for Fastening Process Development: Use of Chemistry and Process Design as Intensification Fields Chemical Engineering & Technology, 2012, 35, 1184-1204, DOI: 10.1002/ceat.201200038
Hessel, V.; Gürsel, I. V.; Wang, Q.; Noël, T. and Lang, J. Potential Analysis of Smart Flow Processing and Micro Process Technology for Fastening Process Development – Use of Chemistry and Process Design as Intensification Fields Chemie Ingenieur Technik, 2012, 84, 660-684, DOI: 10.1002/cite.201200007
Noël, T. Green Is the Future of Chemistry: Report of Taminco's Second Green Footsteps Event at the i-SUP 2012 Green Processing and Synthesis, 2012, 1, DOI: 10.1515/gps-2012-0044
Gürsel, I. V.; Hessel, V.; Wang, Q.; Noël, T. and Lang, J. Window of Opportunity – Potential of Increase in Profitability Using Modular Compact Plants and Micro-Reactor Based Flow Processing Green Processing and Synthesis, 2012, 1, DOI: 10.1515/gps-2012-0046
Bert, K.; Noël, T.; Kimpe, W.; Goeman, J. L. and Van Der Eycken, J. Chiral Imidate–Ferrocenylphosphanes: Synthesis and Application as P,N-ligands in Iridium(i)-Catalyzed Hydrogenation of Unfunctionalized and Poorly Functionalized Olefins Organic & Biomolecular Chemistry, 2012, 10, 8539, DOI: 10.1039/c2ob25871d










