C–H Activation Chemistry

The formation of carbon-carbon bonds is of great importance for the development of pharmaceuticals and other biologically active molecules, and functional materials. In contrast to traditional cross-coupling chemistry, C–H activation requires no prefunctionalization of the substrates. However, the applicability of C–H activation chemistry has been limited mainly by the inert nature of the carbon-hydrogen bond. Our group has developed continuous-flow strategies to boost the reactivity of C–H activation chemistry.

Representative publications: